SirReal1-O-propargyl [1862237-99-7]
HY-107453
CAS Number1862237-99-7
Product group Chemicals
Estimated Purity93.77
Molecular Weight424.54
Overview
- SupplierMedChem Express
- Product NameSirReal1-O-propargyl [1862237-99-7]
- Delivery Days Customer10
- CAS Number1862237-99-7
- CertificationResearch Use Only
- Estimated Purity93.77
- Molecular FormulaC21H20N4O2S2
- Molecular Weight424.54
- Scientific DescriptionSirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 microM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2[1]. SirReal1-O-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C(NC1=NC=C(CC2=CC=CC(OCC#C)=C2)S1)CSC3=NC(C)=CC(C)=N3
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number1862237-99-7
Molecular Weight424.54
- SizePrice
Product group Chemicals
SirReal1-O-propargylORB1987782
CAS Number1862237-99-7
Estimated Purity98.00%
Molecular Weight424.54
- SizePrice