SirReal1-O-propargyl [1862237-99-7]
T18641
CAS Number1862237-99-7
Product group Chemicals
Molecular Weight424.54
Overview
- SupplierTargetMol Chemicals
- Product NameSirReal1-O-propargyl [1862237-99-7]
- Delivery Days Customer999
- CAS Number1862237-99-7
- CertificationResearch Use Only
- Chemical NameSirReal1-O-propargyl
- Molecular FormulaC21H20N4O2S2
- Molecular Weight424.54
- Scientific DescriptionSirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 microM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
- Shelf life instruction3 years
- SMILESO=C(NC1=NC=C(S1)CC=2C=CC=C(OCC#C)C2)CSC=3N=C(C=C(N3)C)C
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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