FACS analysis of K562 cells using GTX82793 SIRT1 antibody [1F3]. Green : SIRT1 Purple : negative control
![ICC/IF analysis of NTERA-2 cells using GTX82793 SIRT1 antibody [1F3]. Green : SIRT1 Red: Actin filaments](https://www.genetex.com/upload/website/prouct_img/normal/GTX82793/GTX82793_20170912_ICCIF_w_23061322_889.webp "ICC/IF analysis of NTERA-2 cells using GTX82793 SIRT1 antibody [1F3]. Green : SIRT1 Red: Actin filaments")
![IHC-P analysis of lung cancer tissue (left) and kidney cancer tissue (right) using GTX82793 SIRT1 antibody [1F3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82793/GTX82793_20170912_IHC-P_w_23061322_489.webp "IHC-P analysis of lung cancer tissue (left) and kidney cancer tissue (right) using GTX82793 SIRT1 antibody [1F3].")
![WB analysis of MCF-7 (1), Jurkat (2), HeLa (3), HEK293 (4) and A549 (5) cell lysate using GTX82793 SIRT1 antibody [1F3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82793/GTX82793_20170912_WB_w_23061322_443.webp "WB analysis of MCF-7 (1), Jurkat (2), HeLa (3), HEK293 (4) and A549 (5) cell lysate using GTX82793 SIRT1 antibody [1F3].")
FACS analysis of K562 cells using GTX82793 SIRT1 antibody [1F3]. Green : SIRT1 Purple : negative control
SIRT1 antibody [1F3]
GTX82793
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetSIRT1
Overview
- SupplierGeneTex
- Product NameSIRT1 antibody [1F3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1F3
- ConjugateUnconjugated
- Gene ID23411
- Target nameSIRT1
- Target descriptionsirtuin 1
- Target synonymsNAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacylase sirtuin-1; regulatory protein SIR2 homolog 1; SIR2; SIR2alpha; SIR2L1; SIR2-like protein 1; sirtuin type 1
- HostMouse
- IsotypeIgG1
- Protein IDQ96EB6
- Protein NameNAD-dependent protein deacetylase sirtuin-1
- Scientific DescriptionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition.Read more
- Citrus Flavanones Upregulate Thyrotroph Sirt1 and Differently Affect Thyroid Nrf2 Expressions in Old-Aged Wistar Rats. Miler M et al., 2020 Aug 5, J Agric Food ChemRead more
- DPP-4 Inhibitor Linagliptin Attenuates Abeta-induced Cytotoxicity through Activation of AMPK in Neuronal Cells. Kornelius E et al., 2015 Jul, CNS Neurosci TherRead more