Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with SIRT1 antibody [SZ04-01] (GTX01139) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
SIRT1 antibody [SZ04-01] - Recombinant antibody Validated
GTX01139
Overview
- SupplierGeneTex
- Product NameSIRT1 antibody [SZ04-01] - Recombinant antibody Validated
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSZ04-01
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID23411
- Target nameSIRT1
- Target descriptionsirtuin 1
- Target synonymsNAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacylase sirtuin-1; regulatory protein SIR2 homolog 1; SIR2; SIR2alpha; SIR2L1; SIR2-like protein 1; sirtuin type 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203