Western blot analysis of extracts of various cell lines using SKP1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using SKP1 Polyclonal Antibody at 1:1000 dilution.
SKP1 Polyclonal Antibody
E-AB-60736
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSKP1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
- UNSPSC12352203