More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/SLD5 antibody [N1C3]

SLD5 antibody [N1C3]

GTX119779
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetGINS4
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    SLD5 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID84296
  • Target name
    GINS4
  • Target description
    GINS complex subunit 4
  • Target synonyms
    DNA replication complex GINS protein SLD5; SLD5; SLD5 homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BRT9
  • Protein Name
    DNA replication complex GINS protein SLD5
  • Scientific Description
    The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients. Liu B et al., 2021 Sep 23, Mol Med
    Read more
  • RecQL4 tethering on the pre-replicative complex induces unscheduled origin activation and replication stress in human cells. Shin G et al., 2019 Nov 1, J Biol Chem
    Read more
  • GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH. Yang R et al., 2019 Nov, Oncogene
    Read more
  • LSH interacts with and stabilizes GINS4 transcript that promotes tumourigenesis in non-small cell lung cancer. Yang R et al., 2019 Jun 28, J Exp Clin Cancer Res
    Read more
  • Embryonic expression of GINS members in the development of the mammalian nervous system. Jia W et al., 2019 Oct, Neurochem Int
    Read more
  • Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication. Li X et al., 2018 Nov 15, Mol Cell
    Read more