SLUG antibody
GTX128796
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSNAI2
Overview
- SupplierGeneTex
- Product NameSLUG antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.18 mg/ml
- ConjugateUnconjugated
- Gene ID6591
- Target nameSNAI2
- Target descriptionsnail family transcriptional repressor 2
- Target synonymsSLUG, SLUGH, SLUGH1, SNAIL2, WS2D, zinc finger protein SNAI2, neural crest transcription factor SLUG, protein snail homolog 2, slug (chicken homolog), zinc finger protein, snail family zinc finger 2, snail homolog 2
- HostRabbit
- IsotypeIgG
- Protein IDO43623
- Protein NameZinc finger protein SNAI2
- Scientific DescriptionThis gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chen WC, Wu CC, Liu YP, et al. Elafin as a Prognostic Marker in Esophageal Squamous Cell Carcinoma: A Pilot Study Using Three-Dimensional Imaging and Genomic Profiling. Cancers (Basel). 2023,15(15). doi: 10.3390/cancers15153825Read this paper
- Huang YH, Chen HK, Hsu YF, et al. Src-FAK Signaling Mediates Interleukin 6-Induced HCT116 Colorectal Cancer Epithelial-Mesenchymal Transition. Int J Mol Sci. 2023,24(7). doi: 10.3390/ijms24076650Read this paper
- Hsu PL, Chien CW, Tang YA, et al. Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis. Sci Adv. 2023,9(15):eade3422. doi: 10.1126/sciadv.ade3422Read this paper
- Zhou Y, Qian W, Li X, et al. NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner. Oxid Med Cell Longev. 2023,2023:7098313. doi: 10.1155/2023/7098313Read this paper
- Chen HH, Yu HI, Rudy R, et al. DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation. iScience. 2021,24(9):103086. doi: 10.1016/j.isci.2021.103086Read this paper
- Lai YW, Hsu WJ, Lee WY, et al. Prognostic Value of a Glycolytic Signature and Its Regulation by Y-Box-Binding Protein 1 in Triple-Negative Breast Cancer. Cells. 2021,10(8). doi: 10.3390/cells10081890Read this paper
- Wang LT, Liu KY, Chiou SS, et al. Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. Cancer Lett. 2021,520:160-171. doi: 10.1016/j.canlet.2021.07.011Read this paper
- Lv F, Du Q, Li L, et al. Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3β/ZEB1 pathway. Eur J Pharmacol. 2021,900:174069. doi: 10.1016/j.ejphar.2021.174069Read this paper
- Li Q, Yu D, Yu Z, et al. TIPE3 promotes non-small cell lung cancer progression via the protein kinase B/extracellular signal-regulated kinase 1/2-glycogen synthase kinase 3β-β-catenin/Snail axis. Transl Lung Cancer Res. 2021,10(2):936-954. doi: 10.21037/tlcr-21-147Read this paper
- Lee KY, Kuo TC, Chou CM, et al. Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling. Cells. 2020,10(1). doi: 10.3390/cells10010028Read this paper
Datasheet
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