SLUG antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX128796
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSNAI2
Overview
- SupplierGeneTex
- Product NameSLUG antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.18 mg/ml
- ConjugateUnconjugated
- Gene ID6591
- Target nameSNAI2
- Target descriptionsnail family transcriptional repressor 2
- Target synonymsneural crest transcription factor SLUG; protein snail homolog 2; SLUG; slug (chicken homolog), zinc finger protein; SLUGH; SLUGH1; snail family zinc finger 2; snail homolog 2; SNAIL2; WS2D; zinc finger protein SNAI2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation. Chen HH et al., 2021 Sep 24, iScienceRead more
- Prognostic Value of a Glycolytic Signature and Its Regulation by Y-Box-Binding Protein 1 in Triple-Negative Breast Cancer. Lai YW et al., 2021 Jul 26, CellsRead more
- Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance. Wang LT et al., 2021 Nov 1, Cancer LettRead more
- Eriodictyol inhibits glioblastoma migration and invasion by reversing EMT via downregulation of the P38 MAPK/GSK-3beta/ZEB1 pathway. Lv F et al., 2021 Jun 5, Eur J PharmacolRead more
- TIPE3 promotes non-small cell lung cancer progression via the protein kinase B/extracellular signal-regulated kinase 1/2-glycogen synthase kinase 3beta-beta-catenin/Snail axis. Li Q et al., 2021 Feb, Transl Lung Cancer ResRead more
- Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling. Lee KY et al., 2020 Dec 25, CellsRead more
- PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer LettRead more
- Sirtuin 7 promotes non-small cell lung cancer progression by facilitating G1/S phase and epithelial-mesenchymal transition and activating AKT and ERK1/2 signaling. Zhao Y et al., 2020 Sep, Oncol RepRead more
- PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition. Wang LT et al., 2020 Feb 5, EMBO RepRead more
- Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9. Chen KY et al., 2019, PLoS OneRead more