
Western Blot Positive WB detected in: HepG2 whole cell lysate, LO2 whole cell lysate All lanes: SMAD7 antibody at 2.3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 47, 24 kDa Observed band size: 47 kDa
SMAD7 Antibody
CSB-PA021793LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetSMAD7
Overview
- SupplierCusabio
- Product NameSMAD7 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4092
- Target nameSMAD7
- Target descriptionSMAD family member 7
- Target synonymsCRCS3, MADH7, MADH8, mothers against decapentaplegic homolog 7, MAD (mothers against decapentaplegic, Drosophila) homolog 7, MAD homolog 8, Mothers against decapentaplegic, drosophila, homolog of, 7, SMAD, mothers against DPP homolog 7, hSMAD7, mothers against DPP homolog 8
- HostRabbit
- IsotypeIgG
- Protein IDO15105
- Protein NameMothers against decapentaplegic homolog 7
- Scientific DescriptionAntagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161






