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SMC5 antibody [N2N3]

Research Use Only
GTX115669
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetSMC5
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Overview

  • Supplier
    GeneTex
  • Product Name
    SMC5 antibody [N2N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID23137
  • Target name
    SMC5
  • Target description
    structural maintenance of chromosomes 5
  • Target synonyms
    hSMC5; SMC protein 5; SMC-5; SMC5 structural maintenance of chromosomes 5-like 1; SMC5L1; structural maintenance of chromosomes protein 5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8IY18
  • Protein Name
    Structural maintenance of chromosomes protein 5
  • Scientific Description
    Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Identification of STAU1 as a regulator of HBV replication by TurboID-based proximity labeling. Wei XF et al., 2022 Jun 17, iScience
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  • Expression of SnoRNA U50A Is Associated with Better Prognosis and Prolonged Mitosis in Breast Cancer. Li JN et al., 2021 Dec 15, Cancers (Basel)
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  • SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes. Hwang G et al., 2017 May 1, Development
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  • Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication. Murphy CM et al., 2016 Sep 13, Cell Rep
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  • Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes. Gomez R et al., 2013 Sep 15, J Cell Sci
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