ProductsBack/SMC5 antibody [N2N3]

SMC5 antibody [N2N3]

Name: SMC5 antibody [N2N3]
SKU: GTX115669_G10
Availability: BackOrder

GTX115669

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Product group Antibodies

TargetSMC5

Overview

Supplier
GeneTex
Product Name
SMC5 antibody [N2N3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID23137
Target name
SMC5
Target description
structural maintenance of chromosomes 5
Target synonyms
ATELS2, SMC5L1, structural maintenance of chromosomes protein 5, SMC protein 5, SMC-5, SMC5 structural maintenance of chromosomes 5-like 1, hSMC5
Host
Rabbit
Isotype
IgG
Protein IDQ8IY18
Protein Name
Structural maintenance of chromosomes protein 5
Scientific Description
Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Wei XF, Fan SY, Wang YW, et al. Identification of STAU1 as a regulator of HBV replication by TurboID-based proximity labeling. iScience. 2022,25(6):104416. doi: 10.1016/j.isci.2022.104416
Read this paper
Li JN, Wang MY, Chen YT, et al. Expression of SnoRNA U50A Is Associated with Better Prognosis and Prolonged Mitosis in Breast Cancer. Cancers (Basel). 2021,13(24). doi: 10.3390/cancers13246304
Read this paper
Hwang G, Sun F, O'Brien M, et al. SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes. Development. 2017,144(9):1648-1660. doi: 10.1242/dev.145607
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Murphy CM, Xu Y, Li F, et al. Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication. Cell Rep. 2016,16(11):2846-2854. doi: 10.1016/j.celrep.2016.08.026
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Gómez R, Jordan PW, Viera A, et al. Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes. J Cell Sci. 2013,126(Pt 18):4239-52. doi: 10.1242/jcs.130195
Read this paper