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SMYD3 antibody

Name: SMYD3 antibody
SKU: GTX121945_G10
Availability: BackOrder

GTX121945

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Product group Antibodies

ReactivityHuman, Mouse

TargetSMYD3

Overview

Supplier
GeneTex
Product Name
SMYD3 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.23 mg/ml
Conjugate
Unconjugated
Gene ID64754
Target name
SMYD3
Target description
SET and MYND domain containing 3
Target synonyms
KMT3E, ZMYND1, ZNFN3A1, bA74P14.1, histone-lysine N-methyltransferase SMYD3, SET and MYND domain-containing protein 3, zinc finger MYND domain-containing protein 1, zinc finger protein, subfamily 3A (MYND domain containing), 1, zinc finger, MYND domain containing 1
Host
Rabbit
Isotype
IgG
Protein IDQ9H7B4
Protein Name
Histone-lysine N-methyltransferase SMYD3
Scientific Description
SMYD3 is a histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex.[supplied by OMIM]
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Sun J, Li Y, Shi M, et al. A Positive Feedback Loop of lncRNA HOXD-AS2 and SMYD3 Facilitates Hepatocellular Carcinoma Progression via the MEK/ERK Pathway. J Hepatocell Carcinoma. 2023,10:1237-1256. doi: 10.2147/JHC.S416946
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Fittipaldi R, Floris P, Proserpio V, et al. The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development. Cells. 2021,10(5). doi: 10.3390/cells10051233
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Yang D, Wang Q, Wei G, et al. Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging. Aging (Albany NY). 2020,12(21):21423-21445. doi: 10.18632/aging.103895
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Fenizia C, Bottino C, Corbetta S, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019,47(3):1278-1293. doi: 10.1093/nar/gky1221
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Chen YJ, Tsai CH, Wang PY, et al. SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression. Sci Rep. 2017,7(1):3842. doi: 10.1038/s41598-017-03385-6
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Proserpio V, Fittipaldi R, Ryall JG, et al. The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy. Genes Dev. 2013,27(11):1299-312. doi: 10.1101/gad.217240.113
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