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SOD1 antibody

GTX100554
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSOD1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SOD1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.15 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6647
  • Target name
    SOD1
  • Target description
    superoxide dismutase 1
  • Target synonyms
    ALS, ALS1, HEL-S-44, IPOA, SOD, STAHP, hSod1, homodimer, superoxide dismutase [Cu-Zn], Cu/Zn superoxide dismutase, SOD, soluble, epididymis secretory protein Li 44, indophenoloxidase A, superoxide dismutase 1, soluble, superoxide dismutase, cystolic
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00441
  • Protein Name
    Superoxide dismutase [Cu-Zn]
  • Scientific Description
    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ayoubi R, Alshafie W, You Z, et al. Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence. F1000Res. 2023,12:391. doi: 10.12688/f1000research.132952.2
    Read this paper
  • Kogami M, Abe S, Nakamura H, et al. Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro. Oncol Lett. 2023,26(1):313. doi: 10.3892/ol.2023.13899
    Read this paper
  • Brinks R, Wruck CJ, Schmitz J, et al. Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice. Antioxidants (Basel). 2023,12(3). doi: 10.3390/antiox12030777
    Read this paper
  • Mesquita PHC, Osburn SC, Godwin JS, et al. Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats. Physiol Rep. 2022,10(24):e15542. doi: 10.14814/phy2.15542
    Read this paper
  • Baek Y, Woo TG, Ahn J, et al. Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation. Commun Biol. 2022,5(1):1085. doi: 10.1038/s42003-022-04017-0
    Read this paper
  • Ramos H, Bogdanov P, Huerta J, et al. Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Antioxidants (Basel). 2022,11(7). doi: 10.3390/antiox11071418
    Read this paper
  • Wu YL, Chang JC, Chao YC, et al. In Vitro Efficacy and Molecular Mechanism of Curcumin Analog in Pathological Regulation of Spinocerebellar Ataxia Type 3. Antioxidants (Basel). 2022,11(7). doi: 10.3390/antiox11071389
    Read this paper
  • Sulistyowati E, Hsu JH, Lee SJ, et al. Potential Actions of Baicalein for Preventing Vascular Calcification of Smooth Muscle Cells In Vitro and In Vivo. Int J Mol Sci. 2022,23(10). doi: 10.3390/ijms23105673
    Read this paper
  • Dogan AE, Hamid SM, Yildirim AD, et al. PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c. J Biol Chem. 2022,298(7):102050. doi: 10.1016/j.jbc.2022.102050
    Read this paper
  • Lai TC, Chen YC, Cheng HH, et al. Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D. Part Fibre Toxicol. 2022,19(1):25. doi: 10.1186/s12989-022-00462-1
    Read this paper

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