SOD1 antibody
GTX100554
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSOD1
Overview
- SupplierGeneTex
- Product NameSOD1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.15 mg/ml
- ConjugateUnconjugated
- Gene ID6647
- Target nameSOD1
- Target descriptionsuperoxide dismutase 1
- Target synonymsALS; ALS1; Cu/Zn superoxide dismutase; epididymis secretory protein Li 44; HEL-S-44; homodimer; hSod1; indophenoloxidase A; IPOA; SOD; SOD, soluble; STAHP; superoxide dismutase [Cu-Zn]; superoxide dismutase 1, soluble; superoxide dismutase, cystolic
- HostRabbit
- IsotypeIgG
- Protein IDP00441
- Protein NameSuperoxide dismutase [Cu-Zn]
- Scientific DescriptionThe protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence.Read more
- Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro.Read more
- Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice.Read more
- Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats.Read more
- Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.Read more
- Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Ramos H et al., 2022 Jul 21, Antioxidants (Basel)Read more
- In Vitro Efficacy and Molecular Mechanism of Curcumin Analog in Pathological Regulation of Spinocerebellar Ataxia Type 3.Read more
- Potential Actions of Baicalein for Preventing Vascular Calcification of Smooth Muscle Cells In Vitro and In Vivo. Sulistyowati E et al., 2022 May 18, Int J Mol SciRead more
- PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c. Dogan AE et al., 2022 Jul, J Biol ChemRead more
- Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D. Lai TC et al., 2022 Mar 29, Part Fibre ToxicolRead more


![FACS analysis of A431 cells using GTX83012 SOD1 antibody [6F5]. Green : SOD1 Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX83012/GTX83012_20170912_FACS_w_23061322_639.webp)
![IHC-P analysis of human breast adenocarcinoma tissue using GTX83592 SOD1 antibody [8B10]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83592/GTX83592_1620_IHC-P_w_23061420_174.webp)

![ICC/IF analysis of Flag-tagged SOD1 wild type or G93A mutant-expressing HEK293 cells using GTX57211 SOD1 (mutant) antibody [MS785], GTX57212 SOD1 (mutant) antibody [MS27] or MS785/MS27 cocktail. Fixation : 4% PFA for 10 min at RT. Permeabilization : 0.2% Triton X-100 for 5 min Dilution : 1microg/ml (12 hours at 4oC)](https://www.genetex.com/upload/website/prouct_img/normal/GTX57211/GTX57211_GTX57211_ICC_IF_1-1_w_23061123_271.webp)
![ICC/IF analysis of Flag-tagged SOD1 wild type or G93A mutant-expressing HEK293 cells using GTX57211 SOD1 (mutant) antibody [MS785], GTX57212 SOD1 (mutant) antibody [MS27] or MS785/MS27 cocktail. Fixation : 4% PFA for 10 min at RT. Permeabilization : 0.2% Triton X-100 for 5 min Dilution : 1microg/ml (12 hours at 4oC)](https://www.genetex.com/upload/website/prouct_img/normal/GTX57212/GTX57212_GTX57212_ICC_IF_1-1_w_23061123_734.webp)
