Sodium/Potassium ATPase beta 1 antibody
GTX113390
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP1B1
Overview
- SupplierGeneTex
- Product NameSodium/Potassium ATPase beta 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID481
- Target nameATP1B1
- Target descriptionATPase Na+/K+ transporting subunit beta 1
- Target synonymsadenosinetriphosphatase; ATP1B; ATPase, Na+/K+ transporting, beta 1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; Na, K-ATPase beta-1 polypeptide; sodium pump subunit beta-1; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain; sodium/potassium-transporting ATPase subunit beta-1; sodium-potassium ATPase subunit beta 1 (non-catalytic)
- HostRabbit
- IsotypeIgG
- Protein IDP05026
- Protein NameSodium/potassium-transporting ATPase subunit beta-1
- Scientific DescriptionThe protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein.Read more
- Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo. Wu SY et al., 2023 Apr, AutophagyRead more
- The cellular prion protein interacts with and promotes the activity of Na,K-ATPases. Williams D et al., 2021, PLoS OneRead more
- The human brain somatostatin interactome: SST binds selectively to P-type family ATPases. Solarski M et al., 2019, PLoS OneRead more
- The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell-cell trans-dimerization of Na,K-ATPase beta1 subunits. Tokhtaeva E et al., 2016 Jun 15, J Cell SciRead more
- Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance. Flodby P et al., 2016 Sep, Am J Respir Cell Mol BiolRead more
- Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury. Kage H et al., 2014 Oct 1, Am J Physiol Lung Cell Mol PhysiolRead more
- Improved functional expression of human cardiac kv1.5 channels and trafficking-defective mutants by low temperature treatment. Ding WG et al., 2014, PLoS OneRead more
- Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Li G et al., 2014 Aug, Am J Respir Cell Mol BiolRead more
- Gene-expression profile and localization of Na+/K(+)-ATPase in rat enamel organ cells. Wen X et al., 2014 Feb, Eur J Oral SciRead more