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Sodium/Potassium ATPase beta 1 antibody

GTX113390
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP1B1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Sodium/Potassium ATPase beta 1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID481
  • Target name
    ATP1B1
  • Target description
    ATPase Na+/K+ transporting subunit beta 1
  • Target synonyms
    adenosinetriphosphatase; ATP1B; ATPase, Na+/K+ transporting, beta 1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; Na, K-ATPase beta-1 polypeptide; sodium pump subunit beta-1; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain; sodium/potassium-transporting ATPase subunit beta-1; sodium-potassium ATPase subunit beta 1 (non-catalytic)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05026
  • Protein Name
    Sodium/potassium-transporting ATPase subunit beta-1
  • Scientific Description
    The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein.
    Read more
  • Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo. Wu SY et al., 2023 Apr, Autophagy
    Read more
  • The cellular prion protein interacts with and promotes the activity of Na,K-ATPases. Williams D et al., 2021, PLoS One
    Read more
  • The human brain somatostatin interactome: SST binds selectively to P-type family ATPases. Solarski M et al., 2019, PLoS One
    Read more
  • The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell-cell trans-dimerization of Na,K-ATPase beta1 subunits. Tokhtaeva E et al., 2016 Jun 15, J Cell Sci
    Read more
  • Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance. Flodby P et al., 2016 Sep, Am J Respir Cell Mol Biol
    Read more
  • Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury. Kage H et al., 2014 Oct 1, Am J Physiol Lung Cell Mol Physiol
    Read more
  • Improved functional expression of human cardiac kv1.5 channels and trafficking-defective mutants by low temperature treatment. Ding WG et al., 2014, PLoS One
    Read more
  • Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Li G et al., 2014 Aug, Am J Respir Cell Mol Biol
    Read more
  • Gene-expression profile and localization of Na+/K(+)-ATPase in rat enamel organ cells. Wen X et al., 2014 Feb, Eur J Oral Sci
    Read more