SORT1 / Sortilin Antibody (Preservative Free)
LS-C815045
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSORT1
Overview
- SupplierLifeSpan BioSciences
- Product NameSORT1 / Sortilin Antibody (Preservative Free)
- Delivery Days Customer14
- Application Supplier NoteApplications should be user optimized.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierIHC-P (1:500 - 1:2000) Applications should be user optimized.
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Estimated Purity...
- Gene ID6272
- Target nameSORT1
- Target descriptionsortilin 1
- Target synonyms100 kDa NT receptor; glycoprotein 95; Gp95; LDLCQ6; neurotensin receptor 3; NT3; NTR3; sortilin
- HostRabbit
- IsotypeIgG
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203

![Binding of Progranulin (human) (rec.) (untagged) (Prod. No. AG-40A-0188Y) to Sortilin (human) (rec.) (His) (Prod. No. AG-40B-0229) is inhibited by the antibody Sortilin (human), mAb (rec.) (blocking) [Latozinemab Bioimilar] (Prod. No. AG-27B-7000PF). Methods: Progranulin (human) (rec.) (untagged) is coated on an ELISA plate at 1 microg/ml. Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar] or an unrelated mAb (Control) is added (starting at 20 microg/ml with a twofold serial dilution) together with 250 ng/ml of Sortilin (rec.) (His) for 1 hour. The binding is detected using an anti-His (HRP) incubated for 30 minutes followed by addition of the substrate TMB. The decreasing ODs observed in the Y axis represent the binding between Progranulin and Sortilin that is inhibited in a dose-dependent manner by Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar]. This inhibition is not observed with the control antibody.](https://adipogen.com/pub/media/catalog/product/a/g/ag-27b-7000pf-binding_blocking_assay-500px.jpg)


