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IHC-Fr analysis of rat neocortex tissue using GTX54854 Sortilin 1 antibody. Panel A : Sortilin appears in cortical neurons (red). Panel B : Staining of interneurons with mouse anti-parvalbumin (PV, green). Panel C : Merge of Sortilin and PV demonstrates separate localization in neocortex.
IHC-Fr analysis of rat neocortex tissue using GTX54854 Sortilin 1 antibody. Panel A : Sortilin appears in cortical neurons (red). Panel B : Staining of interneurons with mouse anti-parvalbumin (PV, green). Panel C : Merge of Sortilin and PV demonstrates separate localization in neocortex.
IHC-Fr analysis of rat neocortex tissue using GTX54854 Sortilin 1 antibody. Panel A : Sortilin appears in cortical neurons (red). Panel B : Staining of interneurons with mouse anti-parvalbumin (PV, green). Panel C : Merge of Sortilin and PV demonstrates separate localization in neocortex.

Sortilin 1 antibody

GTX54854
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSORT1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Sortilin 1 antibody
  • Delivery Days Customer
    7
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.4 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6272
  • Target name
    SORT1
  • Target description
    sortilin 1
  • Target synonyms
    100 kDa NT receptor; glycoprotein 95; Gp95; LDLCQ6; neurotensin receptor 3; NT3; NTR3; sortilin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ99523
  • Protein Name
    Sortilin
  • Scientific Description
    This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding. Sparks RP et al., 2016 Oct 21, Biochem Biophys Res Commun
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  • Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells. Sparks RP et al., 2016 Sep 16, Biochem Biophys Res Commun
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