SOS1 antibody

GeneTex

SOS1 antibody

9

Knockdown/Knockout validation was supported by references (PMID:35688418)

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1.58 mg/ml

Unconjugated

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

GF1; GGF1; GINGF; gingival fibromatosis, hereditary, 1; guanine nucleotide exchange factor; HGF; NS4; son of sevenless homolog 1; SOS-1

Rabbit

IgG

Son of sevenless homolog 1

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203