SP600125

MedChem Express

SP600125 [129-56-6]

10

129-56-6

Research Use Only

99.73

C14H8N2O

220.23

SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis[1][2][3].

O=C1C2=C3C(NN=C3C4=C1C=CC=C4)=CC=C2

-20°C,2°C to 8°C

12352200