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SP600125 [129-56-6]

Research Use Only
T3109
TargetMol Chemicals
CAS Number129-56-6
Product group Chemicals
Molecular Weight220.23
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SP600125 [129-56-6]
  • Delivery Days Customer
    4
  • CAS Number
    129-56-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    SP600125
  • Molecular Formula
    C14H8N2O
  • Molecular Weight
    220.23
  • Scientific Description
    SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
  • Shelf life instruction
    3 years
  • SMILES
    O=C1C2=C3C(NN=C3C3=C1C=CC=C3)=CC=C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Li CH, et al. Enhancement of radiosensitivity by inhibition of c-Jun N-terminal kinase activity in a Lewis lung carcinoma‑bearing subcutaneous tumor mouse model. Oncol Rep. 2016 Dec;36(6):3397-3404.
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