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SP600125 [129-56-6]
T3109
Overview
- SupplierTargetMol Chemicals
- Product NameSP600125 [129-56-6]
- Delivery Days Customer4
- CAS Number129-56-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameSP600125
- Molecular FormulaC14H8N2O
- Molecular Weight220.23
- Scientific DescriptionSP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
- Shelf life instruction3 years
- SMILESO=C1C2=C3C(NN=C3C3=C1C=CC=C3)=CC=C2
- Storage Instruction-20°C
- UNSPSC12352200
References
- Li CH, et al. Enhancement of radiosensitivity by inhibition of c-Jun N-terminal kinase activity in a Lewis lung carcinoma‑bearing subcutaneous tumor mouse model. Oncol Rep. 2016 Dec;36(6):3397-3404.Read more