SPARTIN antibody, Internal

GeneTex

SPARTIN antibody, Internal - KO/KD Validated

9

WB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

SPART

spartin

spartin; spastic paraplegia 20 (Troyer syndrome); SPG20; TAHCCP1; trans-activated by hepatitis C virus core protein 1

Goat

IgG

Spartin

This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]

-20°C or -80°C,2°C to 8°C

12352203