Spike Neutralizing Antibody (Clone G10xA5) (SARS-CoV-2)

BPS Bioscience

Spike Neutralizing Antibody (Clone G10xA5) (SARS-CoV-2)

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The antibody recognizes the B.1.1.529 Omicron variant RBD domain. It has not been tested on other spike variants, on the S1 protein or on the full-length Spike trimer.

Neutralisation/Blocking

Research Use Only

Monoclonal

G10xA5

Human

IgG1

This monoclonal antibody recognizes the SARS-CoV-2 Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2 [Table of Variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using the Spike S1 RBD (B.1.1.529, Omicron Variant) (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience, #78339).

-20°C

12352203