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ProductsBack/ST2 (human):Fc (human) (rec.)
Specific interaction of human ST2 (Prod. No. AG-40A-0059) with recombinant human IL-33. An indirect competitive ELISA was performed as follows; 1) coat microtiter plate wells with hST2-Fc (10microg/ml); 2) add a varying concentrations of hIL-33 with
Specific interaction of human ST2 (Prod. No. AG-40A-0059) with recombinant human IL-33. An indirect competitive ELISA was performed as follows; 1) coat microtiter plate wells with hST2-Fc (10microg/ml); 2) add a varying concentrations of hIL-33 with
Specific interaction of human ST2 (Prod. No. AG-40A-0059) with recombinant human IL-33. An indirect competitive ELISA was performed as follows; 1) coat microtiter plate wells with hST2-Fc (10microg/ml); 2) add a varying concentrations of hIL-33 with

ST2 (human):Fc (human) (rec.)

AG-40A-0059
AdipoGen Life Sciences
Protein IDQ01638
DownloadMSDS
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    ST2 (human):Fc (human) (rec.)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Concentration
    0.5 mg/ml
  • Estimated Purity
    >90%
  • Protein IDQ01638
  • Protein Name
    Interleukin-1 receptor-like 1
  • Scientific Description
    Protein. Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Liquid. 0.2microm-filtered solution in PBS, pH 7.2. Binds to human IL-33. Purity: >90% (SDS-PAGE). The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L. - The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352202

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