STAT5A antibody [N3C3]
GTX103750
ApplicationsFlow Cytometry
Product group Antibodies
TargetSTAT5A
Overview
- SupplierGeneTex
- Product NameSTAT5A antibody [N3C3]
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6776
- Target nameSTAT5A
- Target descriptionsignal transducer and activator of transcription 5A
- Target synonymsepididymis secretory sperm binding protein; MGF; signal transducer and activator of transcription 5A; STAT5
- HostRabbit
- IsotypeIgG
- Protein IDP42229
- Protein NameSignal transducer and activator of transcription 5A
- Scientific DescriptionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A. Uchino Y et al., 2015, Cancer Cell IntRead more


![IHC-P analysis of human colon adenocarcinoma tissue using GTX83547 STAT5A antibody [4H1]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83547/GTX83547_1551_IHC-P_w_23061420_208.webp)

![ELISA analysis of antigen using GTX60652 STAT5A antibody [6D4]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60652/GTX60652_20170912_ELISA_w_23061123_746.webp)

