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Steroid sulfatase antibody [N1C3]

GTX105498
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSTS
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Overview

  • Supplier
    GeneTex
  • Product Name
    Steroid sulfatase antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.43 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID412
  • Target name
    STS
  • Target description
    steroid sulfatase
  • Target synonyms
    ARSC; ARSC1; arylsulfatase C; ASC; ES; estrone sulfatase; SSDD; steroid sulfatase (microsomal), isozyme S; steryl-sulfatase; steryl-sulfate sulfohydrolase; XLI
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08842
  • Protein Name
    Steryl-sulfatase
  • Scientific Description
    The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Simultaneous expression of steroid sulfatase and androgen receptor reduced overall survival of patients with epithelial ovarian tumors. Calvillo-Robledo A et al., 2021 Jul 29, J Ovarian Res
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  • The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors. Secky L et al., 2013, J Drug Deliv
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