STK24 Antibody, FITC conjugated

Cusabio

STK24 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

STK24

serine/threonine kinase 24

epididymis secretory protein Li 95; HEL-S-95; mammalian STE20-like protein kinase 3; MST3; MST3B; serine/threonine kinase 24 (STE20 homolog, yeast); serine/threonine-protein kinase 24; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK3

Rabbit

IgG

Serine/threonine-protein kinase 24

Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on \Thr-442\ and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Human

-20°C or -80°C

12352203