SUN2 antibody

GeneTex

SUN2 antibody

9

Mouse SUN2

Recommended Starting Dilutions:For WB: Use at 1:1000For ICC/IF: Use at 1:500Optimal dilutions should be determined experimentally by the researcher.

Liquid

SUN2

Sad1 and UNC84 domain containing 2

nuclear envelope protein; protein unc-84 homolog B; rab5-interacting protein; rab5IP; Sad1 unc-84 domain protein 2; sad1/unc-84 protein-like 2; SUN domain-containing protein 2; unc-84 homolog B; UNC84B

SUN domain-containing protein 2

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a bridge across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]

-20°C or -80°C,2°C to 8°C

12352203