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Syntenin 1 antibody [C2C3], C-term

GTX108470
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSDCBP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Syntenin 1 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.78 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6386
  • Target name
    SDCBP
  • Target description
    syndecan binding protein
  • Target synonyms
    MDA-9, MDA9, SDCBP1, ST1, SYCL, TACIP18, syntenin-1, melanoma differentiation associated protein-9, pro-TGF-alpha cytoplasmic domain-interacting protein 18, scaffold protein Pbp1, syndecan binding protein (syntenin), syndecan-binding protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00560
  • Protein Name
    Syntenin-1
  • Scientific Description
    The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Korvenlaita N, Gómez-Budia M, Scoyni F, et al. Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia. J Extracell Vesicles. 2023,12(1):e12297. doi: 10.1002/jev2.12297
    Read this paper
  • Haynes BA, Yang LF, Huyck RW, et al. Endothelial-to-Mesenchymal Transition in Human Adipose Tissue Vasculature Alters the Particulate Secretome and Induces Endothelial Dysfunction. Arterioscler Thromb Vasc Biol. 2019,39(10):2168-2191. doi: 10.1161/ATVBAHA.119.312826
    Read this paper
  • Kowal J, Arras G, Colombo M, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A. 2016,113(8):E968-77. doi: 10.1073/pnas.1521230113
    Read this paper