Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TAB1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TAB1 Polyclonal Antibody at dilution 1:40
TAB1 Polyclonal Antibody
E-AB-15186
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTAB1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.2mg/ml
- Scientific DescriptionThe protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.
- UNSPSC12352203