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ProductsBack/TAK1 (phospho Thr184) antibody - Orthogonal Validated
WB analysis of extracts from 293 cells (lane 2) using GTX55449 TAK1 (phospho Thr184) antibody. Left : Primary antibody pre-incubated with the antigen specific peptide Right : Primary antibody
WB analysis of extracts from 293 cells (lane 2) using GTX55449 TAK1 (phospho Thr184) antibody. Left : Primary antibody pre-incubated with the antigen specific peptide Right : Primary antibody
WB analysis of extracts from 293 cells (lane 2) using GTX55449 TAK1 (phospho Thr184) antibody. Left : Primary antibody pre-incubated with the antigen specific peptide Right : Primary antibody

TAK1 (phospho Thr184) antibody - Orthogonal Validated

Research Use Only
GTX55449
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetMAP3K7
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Overview

  • Supplier
    GeneTex
  • Product Name
    TAK1 (phospho Thr184) antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6885
  • Target name
    MAP3K7
  • Target description
    mitogen-activated protein kinase kinase kinase 7
  • Target synonyms
    CSCF; FMD2; MEKK7; mitogen-activated protein kinase kinase kinase 7; TAK1; TGF1a; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Regulation of the regenerative activity of dental pulp stem cells from exfoliated deciduous teeth (SHED) of children by TGF-beta1 is associated with ALK5/Smad2, TAK1, p38 and MEK/ERK signaling. Chang HH et al., 2020 Nov 4, Aging (Albany NY)
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  • Effects of TGF-beta1 on plasminogen activation in human dental pulp cells: Role of ALK5/Smad2, TAK1 and MEK/ERK signalling. Chang MC et al., 2018 Apr, J Tissue Eng Regen Med
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