
WB analysis of human peripheral mononucleocytes lysate using GTX88357 Talin-1 antibody, Internal. Dilution : 1microg/ml Loading : 35microg protein in RIPA buffer
Talin-1 antibody, Internal
GTX88357
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetTLN1
Overview
- SupplierGeneTex
- Product NameTalin-1 antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID7094
- Target nameTLN1
- Target descriptiontalin 1
- Target synonymsILWEQ, TLN, talin-1, talin-1
- HostGoat
- IsotypeIgG
- Protein IDQ9Y490
- Protein NameTalin-1
- Scientific DescriptionThis gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Beaty BT, Wang Y, Bravo-Cordero JJ, et al. Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis. J Cell Biol. 2014,205(5):737-51. doi: 10.1083/jcb.201312046Read this paper




