
WB analysis of Ramos cell lysate using GTX16378 TCL1A antibody. Dilution : 1:1000 Loading : 25microg per lane
TCL1A antibody
GTX16378
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetTCL1A
Overview
- SupplierGeneTex
- Product NameTCL1A antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:10 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8115
- Target nameTCL1A
- Target descriptionTCL1 family AKT coactivator A
- Target synonymsoncogene TCL1; oncogene TCL-1; protein p14 TCL1; T cell leukemia/lymphoma 1A; T-cell leukemia/lymphoma protein 1A; T-cell lymphoma-1; TCL1
- HostRabbit
- IsotypeIgG
- Protein IDP56279
- Protein NameT-cell leukemia/lymphoma protein 1A
- Scientific DescriptionOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203