TCP1 epsilon antibody [PK/29/23/8d]

GeneTex

TCP1 epsilon antibody [PK/29/23/8d]

9

This antibody binds to the canonical isoform 1, binding to the truncated isoform 2 has not been evaluated (UniProt : P48643).

WB: 1/250-1/500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Gel Shift Assay, ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

PK/29/23/8d

1 mg/ml

Unconjugated

CCT5

chaperonin containing TCP1 subunit 5

CCTE; CCT-epsilon; chaperonin containing TCP1, subunit 5 (epsilon); epididymis secretory protein Li 69; HEL-S-69; PNAS-102; T-complex protein 1 subunit epsilon; TCP-1-epsilon

Rat

IgG2a

T-complex protein 1 subunit epsilon

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]

Bovine, Human, Mouse, Rabbit, Rat

-20°C or -80°C,2°C to 8°C

12352203