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TDG antibody [GT311]

GTX631718
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetTDG
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Overview

  • Supplier
    GeneTex
  • Product Name
    TDG antibody [GT311]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT311
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6996
  • Target name
    TDG
  • Target description
    thymine DNA glycosylase
  • Target synonyms
    G/T mismatch-specific thymine DNA glycosylase; hTDG
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDQ13569
  • Protein Name
    G/T mismatch-specific thymine DNA glycosylase
  • Scientific Description
    The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203