
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~58k TR-alpha2 protein using TDP43 antibody (GTX82580).
TDP43 antibody
GTX82580
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetTARDBP
Overview
- SupplierGeneTex
- Product NameTDP43 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23435
- Target nameTARDBP
- Target descriptionTAR DNA binding protein
- Target synonymsALS10; TAR DNA-binding protein 43; TAR DNA-binding protein-43; TDP-43
- HostRabbit
- IsotypeIgG
- Protein IDQ13148
- Protein NameTAR DNA-binding protein 43
- Scientific DescriptionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology. Marsili L et al., 2021 Jul 7, Int J Mol SciRead more