
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~58k TR-α2 protein using TDP43 antibody (GTX82580).
TDP43 antibody
GTX82580
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetTARDBP
Overview
- SupplierGeneTex
- Product NameTDP43 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23435
- Target nameTARDBP
- Target descriptionTAR DNA binding protein
- Target synonymsALS10, TDP-43, TAR DNA-binding protein 43, TAR DNA-binding protein-43
- HostRabbit
- IsotypeIgG
- Protein IDQ13148
- Protein NameTAR DNA-binding protein 43
- Scientific DescriptionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Marsili L, Sharma J, Espay AJ, et al. Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology. Int J Mol Sci. 2021,22(14). doi: 10.3390/ijms22147292Read this paper



![Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT225] (GTX630196) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.](https://www.genetex.com/upload/website/prouct_img/normal/GTX630196/GTX630196_41505_20220805_WB_KO_22080923_561.webp)
![Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT733] (GTX630197) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.](https://www.genetex.com/upload/website/prouct_img/normal/GTX630197/GTX630197_41505_20220805_WB_KO_22080923_274.webp)
![TDP43 antibody [GT6310] detects TDP43 Protein expression by immunohistochemical analysis. Sample: Frozen-sectioned adult mouse cerebellum. Green: TDP43 stained by TDP43 antibody [GT6310] (GTX633973) diluted at 1:250. Red: Calbindin, stained by Calbindin antibody (GTX130856) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).
Antigen Retrieval: Citrate buffer, pH 6.0, 5 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX633973/GTX633973_42730_20170829_IHC-Fr_M_w_23061202_828.webp)
