TET1 antibody [GT1462]
GTX627420
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTET1
Overview
- SupplierGeneTex
- Product NameTET1 antibody [GT1462]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1462
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID80312
- Target nameTET1
- Target descriptiontet methylcytosine dioxygenase 1
- Target synonymsCXXC6, LCX, bA119F7.1, methylcytosine dioxygenase TET1, CXXC finger 6, CXXC zinc finger 6, CXXC-type zinc finger protein 6, leukemia-associated protein with a CXXC domain, ten-eleven translocation 1 gene protein, ten-eleven translocation-1, tet oncogene 1
- HostMouse
- IsotypeIgG2b
- Protein IDQ8NFU7
- Protein NameMethylcytosine dioxygenase TET1
- Scientific DescriptionDioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hsu FM, Wu QY, Fabyanic EB, et al. TET1 facilitates specification of early human lineages including germ cells. iScience. 2023,26(7):107191. doi: 10.1016/j.isci.2023.107191Read this paper
- Lemma RB, Fleischer T, Martinsen E, et al. Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers. Epigenetics Chromatin. 2022,15(1):13. doi: 10.1186/s13072-022-00444-9Read this paper
- Lan Y, Banks KM, Pan H, et al. Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation. Cell Rep. 2021,37(10):110095. doi: 10.1016/j.celrep.2021.110095Read this paper
- Chen W, Liu N, Shen S, et al. Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring. Cell Rep. 2021,37(5):109912. doi: 10.1016/j.celrep.2021.109912Read this paper
- Williamson SM, Ingelson-Filpula WA, Hadj-Moussa H, et al. Epigenetic underpinnings of freeze avoidance in the goldenrod gall moth, Epiblema scudderiana. J Insect Physiol. 2021,134:104298. doi: 10.1016/j.jinsphys.2021.104298Read this paper
- Kim H, Kang Y, Li Y, et al. Ten-eleven translocation protein 1 modulates medulloblastoma progression. Genome Biol. 2021,22(1):125. doi: 10.1186/s13059-021-02352-9Read this paper
- Wan F, Tang YW, Tang XL, et al. TET2 mediated demethylation is involved in the protective effect of triptolide on podocytes. Am J Transl Res. 2021,13(3):1233-1244.Read this paper
- Skrajna A, Goldfarb D, Kedziora KM, et al. Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding. Nucleic Acids Res. 2020,48(17):9415-9432. doi: 10.1093/nar/gkaa544Read this paper
- Peng C, Hou ST, Deng CX, et al. Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes. J Cell Physiol. 2021,236(2):981-996. doi: 10.1002/jcp.29909Read this paper
- Feng W, Chen S, Wang J, et al. DHX33 Recruits Gadd45a To Cause DNA Demethylation and Regulates a Subset of Gene Transcription. Mol Cell Biol. 2020,40(13). doi: 10.1128/MCB.00460-19Read this paper
Datasheet
Related products
Product group Antibodies
TET1 AntibodyCSB-PA847709HA01HU
ApplicationsELISA, ImmunoHistoChemistry
ReactivityHuman
TargetTET1
- SizePrice
Product group Antibodies
TET1 antibody [GT465]GTX629974
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetTET1
- SizePrice
Product group Antibodies
Anti-TET1 Antibody144-63563
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
TargetTET1
- SizePrice
Product group Antibodies
Anti-TET1 AntibodyA13475
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- SizePrice
Product group Antibodies
Anti-TET1 Antibody Picoband(r)A00603-2-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetTET1
- SizePrice
Product group Antibodies
References
TET1 antibodyGTX64332
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetTET1
- SizePrice
Product group Antibodies
References
TET1 antibody [N3C1]GTX124207
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetTET1
- SizePrice