TGF beta 1 antibody

GeneTex

TGF beta 1 antibody

9

The antibody will neutralize the biological activity of recombinant human TGF-β1 and porcine TGF-β1.2.

WB: 0.1-0.2 ug/mL. Neutralizing/Inhibition: ND50:5-30 ng/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, Neutralisation/Blocking

Research Use Only

Polyclonal

Unconjugated

TGFB1

transforming growth factor beta 1

CED; DPD1; IBDIMDE; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; TGFB; TGFbeta; TGF-beta1; TGF-beta-1; transforming growth factor beta1; transforming growth factor beta-1 proprotein

Chicken

IgY

Transforming growth factor beta-1

Transforming Growth Factor Beta 1 is a multifunctional peptide capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed as well as non-neoplastic tissues, release transforming growth factors; and essentially all cells possess a specific TGF beta 1 receptor. The multi-modal nature of TGF beta 1 is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF-Beta-1 whereas hepatocytes, T and B lymphocytes, keratinocytes and many epithelial cells are inhibited by the peptide. TGF beta 1 interacts with Epidermal Growth Factor, Platelet Derived Growth Factor, Fibroblast Growth Factor, and IL2 either by enhancing or antagonizing their characteristic actions. TGF beta 1 plays a fundamental role in tissue growth and differentiation involvement in adipogenesis, myogenesis, chondrogenesis, osteogenesis, epithelial cell differentiation and immune cell function.

Human

-20°C or -80°C,2°C to 8°C

12352203