TGF beta 1 antibody
GTX130023
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTGFB1
Overview
- SupplierGeneTex
- Product NameTGF beta 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.23 mg/ml
- ConjugateUnconjugated
- Gene ID7040
- Target nameTGFB1
- Target descriptiontransforming growth factor beta 1
- Target synonymsCED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta, transforming growth factor beta-1 proprotein, TGF-beta-1, latency-associated peptide, prepro-transforming growth factor beta-1, transforming growth factor beta1
- HostRabbit
- IsotypeIgG
- Protein IDP01137
- Protein NameTransforming growth factor beta-1 proprotein
- Scientific DescriptionTGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chiou WC, Huang GJ, Chang TY, et al. Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway. Biomed Pharmacother. 2023,161:114481. doi: 10.1016/j.biopha.2023.114481Read this paper
- Mang Y, Zhang S, Zhao J, et al. Characteristics of pre-sensitization-related acute antibody-mediated rejection in a rat model of orthotopic liver transplantation. Ann Transl Med. 2022,10(19):1066. doi: 10.21037/atm-22-4311Read this paper
- Fang PH, Lai YY, Chen CL, et al. Cobalt protoporphyrin promotes human keratinocyte migration under hyperglycemic conditions. Mol Med. 2022,28(1):71. doi: 10.1186/s10020-022-00499-0Read this paper
- Cunningham S, McCauley S, Vairamani K, et al. FLASH Proton Pencil Beam Scanning Irradiation Minimizes Radiation-Induced Leg Contracture and Skin Toxicity in Mice. Cancers (Basel). 2021,13(5). doi: 10.3390/cancers13051012Read this paper
- Ho KH, Chen PH, Shih CM, et al. miR-4286 is Involved in Connections Between IGF-1 and TGF-β Signaling for the Mesenchymal Transition and Invasion by Glioblastomas. Cell Mol Neurobiol. 2022,42(3):791-806. doi: 10.1007/s10571-020-00977-1Read this paper
- Chen HY, Ho YJ, Chou HC, et al. TGF-β1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. Chem Biol Interact. 2020,331:109249. doi: 10.1016/j.cbi.2020.109249Read this paper
- Mazumdar A, Urdinez J, Boro A, et al. Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming. Int J Mol Sci. 2020,21(15). doi: 10.3390/ijms21155451Read this paper
- Dantas WS, Roschel H, Murai IH, et al. Exercise-Induced Increases in Insulin Sensitivity After Bariatric Surgery Are Mediated By Muscle Extracellular Matrix Remodeling. Diabetes. 2020,69(8):1675-1691. doi: 10.2337/db19-1180Read this paper
- Ho YJ, Chu SW, Liao EC, et al. Normalization of Tumor Vasculature by Oxygen Microbubbles with Ultrasound. Theranostics. 2019,9(24):7370-7383. doi: 10.7150/thno.37750Read this paper
- Park M, Banga JP, Kim GJ, et al. Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves' ophthalmopathy. Stem Cell Res Ther. 2019,10(1):246. doi: 10.1186/s13287-019-1348-0Read this paper
Datasheet
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