Bio-Connect

TGF beta 1 antibody

GTX130023
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTGFB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    TGF beta 1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.23 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7040
  • Target name
    TGFB1
  • Target description
    transforming growth factor beta 1
  • Target synonyms
    CED; DPD1; IBDIMDE; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; TGFB; TGFbeta; TGF-beta1; TGF-beta-1; transforming growth factor beta1; transforming growth factor beta-1 proprotein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01137
  • Protein Name
    Transforming growth factor beta-1
  • Scientific Description
    TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-beta/TbetaRs signaling pathway.
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  • Characteristics of pre-sensitization-related acute antibody-mediated rejection in a rat model of orthotopic liver transplantation.
    Read more
  • Cobalt protoporphyrin promotes human keratinocyte migration under hyperglycemic conditions. Fang PH et al., 2022 Jun 23, Mol Med
    Read more
  • FLASH Proton Pencil Beam Scanning Irradiation Minimizes Radiation-Induced Leg Contracture and Skin Toxicity in Mice. Cunningham S et al., 2021 Mar 1, Cancers (Basel)
    Read more
  • miR-4286 is Involved in Connections Between IGF-1 and TGF-beta Signaling for the Mesenchymal Transition and Invasion by Glioblastomas. Ho KH et al., 2022 Apr, Cell Mol Neurobiol
    Read more
  • TGF-beta1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. Chen HY et al., 2020 Nov 1, Chem Biol Interact
    Read more
  • Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming. Mazumdar A et al., 2020 Jul 30, Int J Mol Sci
    Read more
  • Exercise-Induced Increases in Insulin Sensitivity After Bariatric Surgery Are Mediated By Muscle Extracellular Matrix Remodeling. Dantas WS et al., 2020 Aug, Diabetes
    Read more
  • Normalization of Tumor Vasculature by Oxygen Microbubbles with Ultrasound. Ho YJ et al., 2019, Theranostics
    Read more
  • Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves ophthalmopathy. Park M et al., 2019 Aug 9, Stem Cell Res Ther
    Read more