
Western blot (WB) analysis of TGFbeta RI pAb at 1:1000 dilution Lane1:The Liver tissue lysate of Rat(40ug) Lane2:The Liver tissue lysate of mouse(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:The Heart tissue lysate of Rat(40ug)
TGF beta Receptor I antibody
GTX57156
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTGFBR1
Overview
- SupplierGeneTex
- Product NameTGF beta Receptor I antibody
- Delivery Days Customer9
- Antibody SpecificityTGFβ RI (E161) pAb detects endogenous levels of TGFβ RI protein.
- Application Supplier NoteWB: 1:500 - 1:1000, ICC/IF: 1:50 - 1:200
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7046
- Target nameTGFBR1
- Target descriptiontransforming growth factor beta receptor 1
- Target synonymsAAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; activin receptor-like kinase 5; ACVRLK4; ALK5; ALK-5; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; serine/threonine-protein kinase receptor R4; SKR4; tbetaR-I; TBRI; TBR-i; TGF-beta receptor type-1; TGFR-1; transforming growth factor beta receptor I; transforming growth factor-beta receptor type I
- HostRabbit
- IsotypeIgG
- Protein IDP36897
- Protein NameTGF-beta receptor type-1
- Scientific DescriptionThe protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFbeta receptor degradation. Hsu HY et al., 2014 Sep 15, OncotargetRead more