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ProductsBack/Thyroid Hormone Receptor beta antibody [J52]
IHC-P analysis of human thyroid tissue using GTX22744 Thyroid Hormone Receptor beta antibody [J52]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:20
IHC-P analysis of human thyroid tissue using GTX22744 Thyroid Hormone Receptor beta antibody [J52]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:20
IHC-P analysis of human thyroid tissue using GTX22744 Thyroid Hormone Receptor beta antibody [J52]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:20

Thyroid Hormone Receptor beta antibody [J52]

GTX22744
GeneTex
ApplicationsGel Shift Assay, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTHRB
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Overview

  • Supplier
    GeneTex
  • Product Name
    Thyroid Hormone Receptor beta antibody [J52]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is specific for the TR beta-1 isoform. This antibody recognizes an epitope in the A/B domain of human TR beta-1, amino acid residues 1-101.
  • Application Supplier Note
    WB: 1:1,000. ICC/IF: 1:20-1:500. IHC-P: 1:20. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Gel Shift Assay, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    J52
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7068
  • Target name
    THRB
  • Target description
    thyroid hormone receptor beta
  • Target synonyms
    C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; THR1; THRB1; THRB2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TRbeta
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP10828
  • Protein Name
    Thyroid hormone receptor beta
  • Scientific Description
    The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203