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ProductsBack/Thyroid Hormone Receptor beta antibody [SPM222]
Immunohistochemistry using GTX17898 on human colon carcinoma at 1/50
Immunohistochemistry using GTX17898 on human colon carcinoma at 1/50
Immunohistochemistry using GTX17898 on human colon carcinoma at 1/50

Thyroid Hormone Receptor beta antibody [SPM222]

Research Use Only
GTX17898
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityCanine, Human
TargetTHRB
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Overview

  • Supplier
    GeneTex
  • Product Name
    Thyroid Hormone Receptor beta antibody [SPM222]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Recognises human thyroid receptor beta, does not recognise alpha 1 and alpha 2 isotypes.
  • Application Supplier Note
    IHC-P: 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SPM222
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7068
  • Target name
    THRB
  • Target description
    thyroid hormone receptor beta
  • Target synonyms
    C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; THR1; THRB1; THRB2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TRbeta
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP10828
  • Protein Name
    Thyroid hormone receptor beta
  • Scientific Description
    The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Canine, Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203