TNF alpha antibody
GTX110520
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTNF
Overview
- SupplierGeneTex
- Product NameTNF alpha antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.28 mg/ml
- ConjugateUnconjugated
- Gene ID7124
- Target nameTNF
- Target descriptiontumor necrosis factor
- Target synonymsDIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F, tumor necrosis factor, APC1 protein, TNF, macrophage-derived, TNF, monocyte-derived, TNF-a, tumor necrosis factor ligand 1F, tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha, tumor necrotic factor alpha
- HostRabbit
- IsotypeIgG
- Protein IDP01375
- Protein NameTumor necrosis factor
- Scientific DescriptionThis gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Locatelli M, Rottoli D, Mahmoud R, et al. Endothelial Glycocalyx of Peritubular Capillaries in Experimental Diabetic Nephropathy: A Target of ACE Inhibitor-Induced Kidney Microvascular Protection. Int J Mol Sci. 2023,24(22). doi: 10.3390/ijms242216543Read this paper
- Huang SC, Wu WJ, Lee YJ, et al. Gastroprotective effects of Machilus zuihoensis Hayata bark against acidic ethanol-induced gastric ulcer in mice. J Tradit Complement Med. 2023,13(5):511-520. doi: 10.1016/j.jtcme.2023.05.006Read this paper
- Chen TC, Lo YC, Li SJ, et al. Assessing traffic-related air pollution-induced fiber-specific white matter degradation associated with motor performance declines in aged rats. Ecotoxicol Environ Saf. 2023,263:115373. doi: 10.1016/j.ecoenv.2023.115373Read this paper
- Gu X, Zhao L, Ye J, et al. 1,25(OH)(2)D(3) ameliorates doxorubicin‑induced cardiomyopathy by inhibiting the NLRP3 inflammasome and oxidative stress. Exp Ther Med. 2023,26(3):413. doi: 10.3892/etm.2023.12112Read this paper
- Torres-Méndez JK, Niño-Narvión J, Martinez-Santos P, et al. Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms. Nutrients. 2023,15(14). doi: 10.3390/nu15143083Read this paper
- Ohnishi H, Zhang Z, Yurube T, et al. Anti-Inflammatory Effects of Adiponectin Receptor Agonist AdipoRon against Intervertebral Disc Degeneration. Int J Mol Sci. 2023,24(10). doi: 10.3390/ijms24108566Read this paper
- Zhang C, Kang Y, Zhang Z, et al. Long-Term Administration of LL-37 Can Induce Irreversible Rosacea-like Lesion. Curr Issues Mol Biol. 2023,45(4):2703-2716. doi: 10.3390/cimb45040177Read this paper
- Chu PC, Huang CS, Ing SZ, et al. Pulsed Focused Ultrasound Reduces Hippocampal Volume Loss and Improves Behavioral Performance in the Kainic Acid Rat Model of Epilepsy. Neurotherapeutics. 2023,20(2):502-517. doi: 10.1007/s13311-023-01363-7Read this paper
- Chiou WC, Huang GJ, Chang TY, et al. Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway. Biomed Pharmacother. 2023,161:114481. doi: 10.1016/j.biopha.2023.114481Read this paper
- Wu R, Zhang L, Xu H, et al. Salvia miltiorrhiza Extract Prevents the Occurrence of Early Atherosclerosis in Apoe -/- Mice via TLR4/ NF-kB Pathway. Cardiovasc Hematol Agents Med Chem. 2023,21(3):232-239. doi: 10.2174/1871525721666230206112134Read this paper
Datasheet
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