TNF-R1 (human):Fc (human) (rec.)

AdipoGen Life Sciences

TNF-R1 (human):Fc (human) (rec.)

10

Research Use Only

1 mg/ml

>95%

TNFRSF1A

TNF receptor superfamily member 1A

CD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60, tumor necrosis factor receptor superfamily member 1A, TNF-R1, TNF-RI, TNFR-I, tumor necrosis factor binding protein 1, tumor necrosis factor receptor type 1, tumor necrosis factor-alpha receptor

Tumor necrosis factor receptor superfamily member 1A

Protein. The extracellular domain of human TNF-R1 (aa 22-211) is fused to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). TNF-R1 is a receptor for TNF-alpha and homotrimeric lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. - TNF-R1 is a receptor for TNF-alpha and homotrimeric lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

-20°C,2°C to 8°C

41116100

Human