ELISA analysis of recombinant human Soluble TNF Receptor II protein using GTX54417 TNF Receptor II antibody [MR2-1]. as capture antibody used in different concentrations.
TNF Receptor II antibody [MR2-1]
GTX54417
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetTNFRSF1B
Overview
- SupplierGeneTex
- Product NameTNF Receptor II antibody [MR2-1]
- Delivery Days Customer9
- Antibody SpecificityThe antibody MR2-1 reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor.
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMR2-1
- Concentration100 ug/ml
- ConjugateUnconjugated
- Gene ID7133
- Target nameTNFRSF1B
- Target descriptionTNF receptor superfamily member 1B
- Target synonymsCD120b; p75; p75 TNF receptor; p75TNFR; p80 TNF-alpha receptor; soluble TNFR1B variant 1; TBPII; TNFBR; TNFR1B; TNFR2; TNF-R2; TNF-R75; TNFR80; TNF-RII; TNF-R-II; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor type II
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Monkey, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203