Immunohistochemistry of paraffin-embedded Rat brain using TNFSF12 Polyclonal Antibody at dilution of 1:100 (20x lens).
Immunohistochemistry of paraffin-embedded Rat brain using TNFSF12 Polyclonal Antibody at dilution of 1:100 (20x lens).
TNFSF12 Polyclonal Antibody
E-AB-61047
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTNFSF12 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
- UNSPSC12352203