Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TNK2 Polyclonal Antibody at dilution 1:70
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TNK2 Polyclonal Antibody at dilution 1:70
TNK2 Polyclonal Antibody
E-AB-15457
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTNK2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThis gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
- UNSPSC12352203