The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA445195(TRAF1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
TRAF1 Antibody
CSB-PA445195
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTRAF1
Overview
- SupplierCusabio
- Product NameTRAF1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7185
- Target nameTRAF1
- Target descriptionTNF receptor associated factor 1
- Target synonymsEBI6; Epstein-Bar virus-induced protein 6; MGC:10353; TNF receptor-associated factor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ13077
- Protein NameTNF receptor-associated factor 1
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203