TRAF3 Antibody, Biotin conjugated
CSB-PA024148LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetTRAF3
Overview
- SupplierCusabio
- Product NameTRAF3 Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- Gene ID7187
- Target nameTRAF3
- Target descriptionTNF receptor associated factor 3
- Target synonymsCAP1; CAP-1; CD40 associated protein 1; CD40 binding protein; CD40 receptor associated factor 1; CD40bp; CRAF1; IIAE5; LAP1; LMP1-associated protein 1; RING-type E3 ubiquitin transferase TRAF3; RNF118; TNF receptor-associated factor 3
- HostRabbit
- IsotypeIgG
- Protein IDQ13114
- Protein NameTNF receptor-associated factor 3
- Scientific DescriptionRegulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote \Lys-63\-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203