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Transgelin antibody

GTX101608
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTAGLN
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Overview

  • Supplier
    GeneTex
  • Product Name
    Transgelin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.47 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6876
  • Target name
    TAGLN
  • Target description
    transgelin
  • Target synonyms
    22 kDa actin-binding protein; epididymis secretory sperm binding protein; SM22; SM22-alpha; SMCC; smooth muscle protein 22-alpha; TAGLN1; transgelin; transgelin variant 2; WS3-10
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ01995
  • Protein Name
    Transgelin
  • Scientific Description
    The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Canonical transient receptor potential 6 channel deficiency promotes smooth muscle cells dedifferentiation and increased proliferation after arterial injury. Smith AH et al., 2020, JVS Vasc Sci
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  • Chemokine mediated signalling within arteries promotes vascular smooth muscle cell recruitment. Stratman AN et al., 2020 Dec 4, Commun Biol
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  • Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress. Hao W et al., 2018 Jan 15, Life Sci
    Read more
  • The role of pericytic laminin in blood brain barrier integrity maintenance. Gautam J et al., 2016 Nov 3, Sci Rep
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  • Biomarker discovery for neuroendocrine cervical cancer. Lin LH et al., 2014 Jul, Electrophoresis
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  • Mechanisms underlying a decrease in KCl-induced contraction after long-term serum-free organ culture of rat isolated mesenteric artery. Morita T et al., 2014 Jul, J Vet Med Sci
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  • Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence. Hampl V et al., 2013 Sep, EMBO Mol Med
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