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Transgelin antibody

Name: Transgelin antibody
SKU: GTX101608_G10
Availability: BackOrder

GTX101608

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetTAGLN

Overview

Supplier
GeneTex
Product Name
Transgelin antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.47 mg/ml
Conjugate
Unconjugated
Gene ID6876
Target name
TAGLN
Target description
transgelin
Target synonyms
22 kDa actin-binding protein; epididymis secretory sperm binding protein; SM22; SM22-alpha; SMCC; smooth muscle protein 22-alpha; TAGLN1; transgelin; transgelin variant 2; WS3-10
Host
Rabbit
Isotype
IgG
Protein IDQ01995
Protein Name
Transgelin
Scientific Description
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Canonical transient receptor potential 6 channel deficiency promotes smooth muscle cells dedifferentiation and increased proliferation after arterial injury. Smith AH et al., 2020, JVS Vasc Sci
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Chemokine mediated signalling within arteries promotes vascular smooth muscle cell recruitment. Stratman AN et al., 2020 Dec 4, Commun Biol
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Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress. Hao W et al., 2018 Jan 15, Life Sci
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The role of pericytic laminin in blood brain barrier integrity maintenance. Gautam J et al., 2016 Nov 3, Sci Rep
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Biomarker discovery for neuroendocrine cervical cancer. Lin LH et al., 2014 Jul, Electrophoresis
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Mechanisms underlying a decrease in KCl-induced contraction after long-term serum-free organ culture of rat isolated mesenteric artery. Morita T et al., 2014 Jul, J Vet Med Sci
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Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence. Hampl V et al., 2013 Sep, EMBO Mol Med
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