Transglutaminase 2 antibody [N3C3]
GTX111702
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTGM2
Overview
- SupplierGeneTex
- Product NameTransglutaminase 2 antibody [N3C3]
- Delivery Days Customer9
- Antibody SpecificityKnockdown/Knockout validation was supported by references (PMID:26956429).
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.05 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7052
- Target nameTGM2
- Target descriptiontransglutaminase 2
- Target synonymsC polypeptide, protein-glutamine-gamma-glutamyltransferase; erythrocyte transglutaminase; G(h); heart G alpha(h); hhG alpha(h); hTG2; isopeptidase TGM2; protein G alpha(h); protein-glutamine deamidase TGM2; protein-glutamine dopaminyltransferase TGM2; protein-glutamine gamma-glutamyltransferase 2; protein-glutamine histaminyltransferase TGM2; protein-glutamine noradrenalinyltransferase TGM2; protein-glutamine serotonyltransferase TGM2; TG(C); TGase C; TGase H; TGase II; TGase-2; TGC; tissue transglutaminase; transglutaminase C; transglutaminase H; transglutaminase II; tTG; tTgase
- HostRabbit
- IsotypeIgG
- Protein IDP21980
- Protein NameProtein-glutamine gamma-glutamyltransferase 2
- Scientific DescriptionTransglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis. Xu P et al., 2022 Feb 1, Cell MetabRead more
- Calcium-dependent activation of transglutaminase 2 by nanosecond pulsed electric fields. Morotomi-Yano K et al., 2017 Jul, FEBS Open BioRead more
- Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. Yeo SY et al., 2016 Mar 9, ElifeRead more
- Fibroblast-endothelial partners for vascularization strategies in tissue engineering. Costa-Almeida R et al., 2015 Mar, Tissue Eng Part ARead more