TREX1 antibody

GeneTex

TREX1 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.75 mg/ml

Unconjugated

TREX1

three prime repair exonuclease 1

3' repair exonuclease 1; 3'-5' exonuclease TREX1; AGS1; CRV; deoxyribonuclease III; DNase III; DRN3; HERNS; RVCLS; three-prime repair exonuclease 1

Rabbit

IgG

Three-prime repair exonuclease 1

This gene encodes the major 3->5 DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3 ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203