TRIB3 Rabbit mAb

Biorbyt

TRIB3 Rabbit mAb

10

ImmunoPrecipitation, Western Blot

WB 1:1000~1:5000 IP 1:20 IP, WB

Research Use Only

Monoclonal

Unconjugated

TRIB3

tribbles pseudokinase 3

C20orf97, NIPK, SINK, SKIP3, TRB3, tribbles homolog 3, TRB-3, neuronal cell death inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, p65-interacting inhibitor of NF-kappaB

Rabbit

IgG

Tribbles homolog 3

Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the Thr-308 phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.

Human

-20°C,2°C to 8°C

12352203