TRIM5 (alpha isoform) antibody, Internal

GeneTex

TRIM5 (alpha isoform) antibody, Internal

7

This antibody is expected to recognise isoform alpha (NP_149023.1) only.

IHC-P: 3-6microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

TRIM5

tripartite motif containing 5

ring finger protein 88; RING-type E3 ubiquitin transferase TRIM5; RNF88; TRIM5alpha; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing protein 5

Goat

IgG

Tripartite motif-containing protein 5

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203